Adrenergic Agonist Drugs MCQs with Answers Free 2022

Adrenergic Agonist Drugs MCQs with Answers 2022 : Adrenergic agonists are drugs that work by mimicking the functioning of the sympathetic nervous system—the part of the nervous system that increases heart rate, blood pressure, breathing rate, and eye pupil size. Adrenergic agonists drug is type of Adrenergic drugs that can help do the following: increase blood pressure. constrict blood vessels. open the airways leading to the lungs.

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Adrenergic Agonists Drugs MCQs with Answers Free 2022 [Practice Now]


  1. Which of the following drugs is a nonselective alfa receptor antagonist?
    a) Prazosin
    b) Phentolamine
    c) Metoprolol
    d) Reserpine
  2. Indicate the alfa1-selective antagonist:
    a) Phentolamine
    b) Dihydroergotamine
    c) Prazosin
    d) Labetalol
  3. Which of the following agents is an alfa2–selective antagonist?
    a) Yohimbine
    b) Tamsulosin
    c) Tolazoline
    d) Prazosin
  4. Indicate the irreversible alfa receptor antagonist:
    a) Tolazoline
    b) Labetalol
    c) Prazosin
    d) Phenoxybenzamine
  5. Which of the following drugs is an nonselective beta receptor antagonist?
    a) Metoprolol
    b) Atenolol
    c) Propranolol
    d) Acebutolol
  6. Indicate the beta1-selective antagonist:
    a) Propranolol
    b) Metoprolol
    c) Carvedilol
    d) Sotalol
  7. Which of the following agents is a beta2–selective antagonist?
    a) Tolazolin
    b) Pindolol
    c) Ergotamin
    d) Butoxamine
  8. Indicate the beta adrenoreceptor antagonist, which has partial beta–agonist activity:
    a) Propranolol
    b) Metoprolol
    c) Pindolol
    d) Betaxolol
  9. Which of the following drugs is a reversible nonselective alfa, beta antagonist?
    a) Labetalol
    b) Phentolamine
    c) Metoprolol
    d) Propranolol
  10. Indicate the indirect-acting adrenoreceptor blocking drug:
    a) Tolazoline
    b) Reserpine
    c) Carvedilol
    d) Prazosin
  11. The principal mechanism of action of adrenoreceptor antagonists is:
    a) Reversible or irreversible interaction with adrenoreceptors
    b) Depletion of the storage of catecholamines
    c) Blockade of the amine reuptake pumps
    d) Nonselective MAO inhibition
  12. Characteristics of alfa-receptor antagonists include all of the following EXCEPT:
    a) They cause a fall in peripheral resistance and blood pressure
    b) They cause epinephrine reversal (convert a pressor response to a depressor response)
    c) Bronchospasm
    d) They may cause postural hypotension and reflex tachycardia
  13. Which of the following drugs is an imidazoline derivative and a potent competitive antagonist at both alfa1 and alfa2 receptors?
    a) Prazosin
    b) Labetalol
    c) Phenoxybenzamine
    d) Phentolamine
  14. Characteristics of phentolamine include all of the following EXCEPT:
    a) Reduction in peripheral resistance
    b) Stimulation of responses to serotonin
    c) Tachycardia
    d) Stimulation of muscarinic, H1 and H2 histamine receptors
  15. The principal mechanism of phentolamine-induced tachycardia is:
    a) Antagonism of presynaptic alfa2 receptors enhances norepinephrine release, which causes cardiac stimulation via unblocked beta receptors
    b) Baroreflex mechanism
    c) Direct effect on the heart by stimulation of beta1 receptors
    d) Inhibition of transmitter reuptake at noradrenergic synapses
  16. Nonselective alfa-receptor antagonists are most useful in the treatment of:
    a) Asthma
    b) Cardiac arrhythmias
    c) Pheochromocytoma
    d) Chronic hypertension
  17. The main reason for using alfa-receptor antagonists in the management of pheochromocytoma is:
    a) Inhibition of the release of epinephrine from the adrenal medulla
    b) Blockade of alfa2 receptors on vascular smooth muscle results in epinephrine stimulation of unblocked alfa2 receptors
    c) Direct interaction with and inhibition of beta2 adrenoreceptors
    d) Antagonism to the release of renin
  18. Which of the following drugs is useful in the treatment of pheochromocytoma?
    a) Phenylephrine
    b) Propranolol
    c) Phentolamine
    d) Epinephrine
  19. Indicate adrenoreceptor antagonist agents, which are used for the management of pheochromocytoma:
    a) Selective beta2-receptor antagonists
    b) Nonselective beta-receptor antagonists
    c) Indirect-acting adrenoreceptor antagonist drugs
    d) Αlfa-receptor antagonists
  20. The principal adverse effects of phentolamine include all of the following EXCEPT:
    a) Diarrhea
    b) Bradycardia
    c) Arrhythmias
    d) Myocardial ischemia
  21. Indicate the reversible nonselective alfa-receptor antagonist, which is an ergot derivative:
    a) Ergotamine
    b) Prazosin
    c) Phenoxybenzamine
    d) Carvedilol
  22. Indicate an alfa-receptor antagonist, which binds covalently to alfa receptors, causing irreversible blockade of long duration (14-48 hours or longer):
    a) Phentolamine
    b) Phenoxybenzamine
    c) Ergotamine
    d) Prazosin
  23. Compared with phentolamine, prazosin has all of the following features EXCEPT:
    a) Irreversible blockade of alfa receptors
    b) Highly selective for alfa1 receptors
    c) The relative absence of tachycardia
    d) Persistent block of alfa1 receptors
  24. Which of the following statements is not correct?
    a) There are at least three subtypes of alfa1 receptors, designated alfa1a, alfa1b and alfa1d
    b) ALFA1a subtype mediates prostate smooth muscle contraction
    c) ALFA1b subtype mediates vascular smooth muscle contraction
    d) ALFA1a subtype mediates both vascular and prostate smooth muscle contraction
  25. Indicate an alfa1 adrenoreceptor antagonist, which has great selectivity for alfa1a subtype:
    a) Prazosin
    b) Tamsulosin
    c) Phenoxybenzamine
    d) Phentolamine
  26. Subtype-selective alfa1 receptor antagonists such as tamsulosin, terazosin, alfusosin are efficacious in:
    a) Hyperthyroidism
    b) Cardiac arrhythmias
    c) Benign prostatic hyperplasia (BPH)
    d) Asthma
  27. Indicate an alfa receptor antagonist, which is an efficacious drug in the treatment of mild to moderate systemic
    hypertension:
    a) Phentolamine
    b) Tolazoline
    c) Ergotamine
    d) Prazosin
  28. Which of the following alfa receptor antagonists is useful in reversing the intense local vasoconstriction caused by inadvertent infiltration of norepinephrine into subcutaneous tissue during intravenous administration?
    a) Propranolol
    b) Phentolamine
    c) Tamsulosin
    d) Ergotamine
  29. Beta-blocking drugs-induced chronically lower blood pressure may be associated with theirs effects on:
    a) The heart
    b) The blood vessels
    c) The renin-angiotensin system
    d) All of the above
  30. Characteristics of beta-blocking agents include all of the following EXCEPT:
    a) They occupy beta receptors and competitively reduce receptor occupancy by catecholamines or other beta agonists
    b) They do not cause hypotension in individuals with normal blood pressure
    c) They induce depression and depleted stores of catecholamines
    d) They can cause blockade in the atrioventricular node
  31. Beta-receptor antagonists have all of the following cardiovascular effects EXCEPT:
    a) The negative inotropic and chronotropic effects
    b) Acute effects of these drugs include a fall in peripheral resistance
    c) Vasoconstriction
    d) Reduction of the release of renin
  32. Beta-blocking agents have all of the following effects except:
    a) Increase plasma concentrations of HDL and decrease of VLDL
    b) Bronchoconstriction
    c) Decrease of aqueous humor prodaction
    d) “membrane-stabilizing” action
  33. Beta-receptor antagonists cause:
    a) Stimulation of lipolysis
    b) Stimulation of gluconeogenesis
    c) Inhibition of glycogenolysis
    d) Stimulation of insulin secretion
  34. Propranolol has all of the following cardiovascular effects EXCEPT:
    a) It decreases cardiac work and oxygen demand
    b) It reduces blood flow to the brain
    c) It inhibits the renin secretion
    d) It increases the atrioventricular nodal refractory period
  35. Propranolol-induced adverse effects include all of the following EXCEPT:
    a) Bronchoconstriction
    b) “supersensitivity” of beta-adrenergic receptors (rapid withdrawal)
    c) Hyperglycemia
    d) Sedation, sleep disturbances, depression and sexual dysfunction
  36. Propranolol is used in the treatment all of the following diseases EXCEPT:
    a) Cardiovascular diseases
    b) Hyperthyroidism
    c) Migraine headache
    d) Bronchial asthma
  37. Metoprolol and atenolol:
    a) Are members of the beta1-selective group
    b) Are nonselective beta antagonists
    c) Have intrinsic sympathomimetic activity
    d) Have an anesthetic action
  38. Which of the following beta receptor antagonists is preferable in patients with asthma, diabetes or peripheral vascular diseases?
    a) Propranolol
    b) Metoprolol
    c) Nadolol
    d) Timolol
  39. Indicate a beta receptor antagonist, which has very long duration of action:
    a) Metoprolol
    b) Propranolol
    c) Nadolol
    d) Pindolol
  40. Indicate a beta1-selective receptor antagonist, which has very long duration of action:
    a) Betaxolol
    b) Sotalol
    c) Nadolol
    d) Metoprolol
  41. Which of the following drugs is a nonselective beta-blocker without intrinsic sympathomimetic or local anesthetic activity
    and used for the treatment of life-threatening ventricular arrhythmias?
    a) Propranolol
    b) Oxprenolol
    c) Sotalol
    d) Atenolol
  42. Indicate a beta receptor antagonist with intrinsic sympathomimetic activity:
    a) Propranolol
    b) Oxprenolol
    c) Metoprolol
    d) Carvedilol
  43. Pindolol, oxprenolol have all of the following properties EXCEPT:
    a) They are nonselective beta antagonists
    b) They have no partial agonist activity
    c) They are less likely to cause bradycardia and abnormalities in plasma lipids
    d) They are effective in hypertension and angina
  44. Which of the following drugs has both alfa1-selective and beta-blocking effects?
    a) Labetalol
    b) Betaxolol
    c) Propranolol
    d) Timolol
  45. Characteristics of carvedilol include all of the following EXCEPT:
    a) It is a beta1-selective antagonist
    b) It has both alfa1-selective and beta-blocking effects
    c) It attenuates oxygen free radical-initiated lipid peroxidation
    d) It inhibits vascular smooth muscle mitogenesis
  46. Indicate the adrenoreceptor antagonist drug, which is a rauwolfia alkaloid:
    a) Prazosin
    b) Propranolol
    c) Reserpine
    d) Phentolamine
  47. Characteristics of reserpine include all of the following EXCEPT:
    a) It inhibits the uptake of norepinephrine into vesicles and MAO
    b) It decreases cardiac output, peripheral resistance and inhibits pressor reflexes
    c) It may cause a transient sympathomimetic effect
    d) It depletes stores of catecholamines and serotonin in the brain
  48. Indicate a beta-blocker, which is particularly efficacious in thyroid storm:
    a) Pindolol
    b) Sotalol
    c) Phentolamine
    d) Propranolol
  49. Beta-receptor blocking drugs are used in the treatment all of the following diseases EXCEPT:
    a) Hypertension, ischemic heart disease, cardiac arrhythmias
    b) Glaucoma
    c) Pheochromocytoma
    d) Hyperthyroidism
  50. Beta-blocker-induced adverse effects include all of the following EXCEPT:
    a) Bronchoconstriction
    b) Depression of myocardial contractility and excitability
    c) “supersensitivity” of beta-receptors associated with rapid withdrawal of drugs
    d) Hyperglycemia

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Adrenergic Agonists Drugs MCQs with Answers Free 2022 : ANSWER KEY

If you find any Question or Answer wrong , then you can mention in the comment below.

01. –   b   11. –   a   21. –   a   31. –   c    41. –  a  
02. –   c   12. –   c   22. –   b   32. –   b    42. –  c  
03. –   a   13. –   d   23. –   a   33. –   a    43. –  b    
04. –   d   14. –   b   24. –   d   34. –   b   44. –  a  
05. –   c   15. –   a   25. –   b   35. –   c     45. –  a 
06. –   b   16. –   a   26. –   c   36. –   d    46. –  c  
07. –   d   17. –   c   27. –   c   37. –   a    47. –  a  
08. –   c   18. –   b   28. –   d   38. –   b    48. –  d  
09. –   a   19. –   c   29. –   b   39. –   b     49. –  c  
10. –   b   20. –   b   30. –   d   40. –   c    50. –  d  

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