Anaesthesia MCQs with Answers Free 2022

The meaning of Anaesthesia is “loss of sensation”. Anaesthesia is the drug which is use to make you unable to feel pain during medical operations. In brief,  Anaesthetics are used during tests and surgical operations to numb sensation in certain areas of the body or induce sleep. This prevents pain and discomfort, and enables a wide range of medical procedures to be carried out.

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So, this post is all about clearing comfusion about Anesthesia . Here some Multiple Choice Questions are shed below. Practice these Questions,  it will  clear your concepts . These MCQs are very useful for GPAT, B-Pharma, D-Pharma, NIPER etc.


Anesthesia MCQs with Answers Free 2022 [Practice Now]


  1. Local anesthetics produce:
    a) Analgesia, amnesia, loss of consciousness
    b) Blocking pain sensation without loss of consciousness
    c) Alleviation of anxiety and pain with an altered level of consciousness
    d) A stupor or somnolent state
  2. A good local anesthetic agent shouldn’t cause:
    a) Local irritation and tissue damage
    b) Systemic toxicity
    c) Fast onset and long duration of action
    d) Vasodilatation
  3. Most local anesthetic agents consist of:
    a) Lipophylic group (frequently an aromatic ring)
    b) Intermediate chain (commonly including an ester or amide)
    c) Amino group
    d) All of the above
  4. Which one of the following groups is responsible for the duration of the local anesthetic action?
    a) Intermediate chain
    b) Lipophylic group
    c) Ionizable group
    d) All of the above
  5. Indicate the local anesthetic agent, which has a shorter duration of action:
    a) Lidocaine
    b) Procaine
    c) Bupivacaine
    d) Ropivacaine
  6. Which one of the following groups is responsible for the potency and the toxicity of local anesthetics?
    a) Ionizable group
    b) Intermediate chain
    c) Lipophylic group
    d) All of the above
  7. Indicate the drug, which has greater potency of the local anesthetic action:
    a) Lidocaine
    b) Bupivacaine
    c) Procaine
    d) Mepivacaine
  8. Ionizable group is responsible for:
    a) The potency and the toxicity
    b) The duration of action
    c) The ability to diffuse to the site of action
    d) All of the above
  9. Which one of the following local anesthetics is an ester of benzoic acid?
    a) Lidocaine
    b) Procaine
    c) Ropivacaine
    d) Cocaine
  10. Indicate the local anesthetic, which is an ester of paraaminobenzoic acid:
    a) Mepivacaine
    b) Cocaine
    c) Procaine
    d) Lidocaine
  11. Which of the following local anesthetics is an acetanilide derivative?
    a) Tetracaine
    b) Lidocaine
    c) Cocaine
    d) Procaine
  12. Indicate the local anesthetic, which is a toluidine derivative:
    a) Lidocaine
    b) Bupivacaine
    c) Prilocaine
    d) Procaine
  13. Which of the following local anesthetics is a thiophene derivative?
    a) Procaine
    b) Ultracaine
    c) Lidocaine
    d) Mepivacaine
  14. Local anesthetics are:
    a) Weak bases
    b) Weak acids
    c) Salts
    d) None of the above
  15. For therapeutic application local anesthetics are usually made available as salts for the reasons of:
    a) Less toxicity and higher potency
    b) Higher stability and greater lipid solubility
    c) Less local tissue damage and more potency
    d) More stability and greater water solubility
  16. Which of the following statements is not correct for local anesthetics?
    a) In a tissue they exist either as an uncharged base or as a cation
    b) A charged cationic form penetrates biologic membranes more readily than an uncharged form
    c) Local anesthetics are much less effective in inflamed tissues
    d) Low ph in inflamed tissues decreases the dissociation of nonionized molecules
  17. Which one of the following statements about the metabolism of local anesthetics is incorrect?
    a) Metabolism of local anesthetics occurs at the site of administration
    b) Metabolism occurs in the plasma or liver but not at the site of administration
    c) Ester group of anesthetics like procaine, are metabolized systemically by pseudocholinesterase
    d) Amides such as lidocaine, are metabolized in the liver by microsomal mixed function oxidases
  18. Indicate the anesthetic agent of choice in patient with a liver disease:
    a) Lidocaine
    b) Bupivacaine
    c) Procaine
    d) Etidocaine
  19. Which of the following local anesthetics is preferable in patient with pseudocholinesterase deficiency?
    a) Procaine
    b) Ropivacaine
    c) Tetracaine
    d) Benzocaine
  20. The primary mechanism of action of local anesthetics is:
    a) Activation of ligand-gated potassium channels
    b) Blockade of voltage-gated sodium channels
    c) Stimulation of voltage-gated N-type calcium channels
    d) Blockade the GABA-gated chloride channels
  21. Which of the following local anesthetics is more water-soluble?
    a) Tetracaine
    b) Etidocaine
    c) Procaine
    d) Bupivacaine
  22. Indicate the local anesthetic, which is more lipid-soluble:
    a) Bupivacaine
    b) Lidocaine
    c) Mepivacaine
    d) Procaine
  23. The more lipophylic drugs:
    a) Are more potent
    b) Have longer duration of action
    c) Bind more extensively to proteins
    d) All of the above
  24. Which of the following fibers is the first to be blocked?
    a) Type A alpha fibers
    b) B and C fibers
    c) Type A beta fibers
    d) Type A gamma fibers
  25. Indicate the function, which the last to be blocked:
    a) Pain, temperature
    b) Muscle spindles
    c) Motor function
    d) Touch, pressure
  26. Which of the following fibers participates in high-frequency pain transmission?
    a) Type A delta and C fibers
    b) Type A alpha fibers
    c) Type B fibers
    d) Type A beta fibers
  27. Which of the following local anesthetics is an useful antiarrhythmic agent?
    a) Cocaine
    b) Lidocaine
    c) Bupivacaine
    d) Ropivacaine
  28. Indicate the route of local anesthetic administration, which is associated with instillation within epidural or subarachnoid spaces:
    a) Topical anesthesia
    b) Infiltrative anesthesia
    c) Regional anesthesia
    d) Spinal anesthesia
  29. The choice of a local anesthetic for specific procedures is usually based on:
    a) The duration of action
    b) Water solubility
    c) Capability of rapid penetration through the skin or mucosa with limited tendency to diffuse away from the site of application
    d) All of the above
  30. Which of the following local anesthetics is a short-acting drug?
    a) Procaine
    b) Tetracaine
    c) Bupivacaine
    d) Ropivacaine
  31. Indicate the local anesthetic, which is a long-acting agent:
    a) Lidocaine
    b) Bupivacaine
    c) Procaine
    d) Mepivacaine
  32. The anesthetic effect of the agents of short and intermediate duration of action can not be prolonged by adding:
    a) Epinephrine
    b) Norepinephrine
    c) Dopamine
    d) Phenylephrine
  33. A vasoconstrictor does not:
    a) Retard the removal of drug from the injection site
    b) Hence the chance of toxicity
    c) Decrease the blood level
    d) Reduce a local anesthetic uptake by the nerve
  34. Vasoconstrictors are less effective in prolonging anesthetic properties of:
    a) Procaine
    b) Bupivacaine
    c) Lidocaine
    d) Mepivacaine
  35. Which of the following local anesthetics is only used for surface or topical anesthesia?
    a) Cocaine
    b) Tetracaine
    c) Procaine
    d) Bupivacaine
  36. Indicate the local anesthetic, which is mainly used for regional nerve block anesthesia:
    a) Dibucaine
    b) Bupivacaine
    c) Tetracaine
    d) Cocaine
  37. Which of the following local anesthetics is used for infiltrative and regional anesthesia?
    a) Procaine
    b) Lidocaine
    c) Mepivacaine
    d) All of the above
  38. Indicate the local anesthetic, which is used for spinal anesthesia:
    a) Tetracaine
    b) Cocaine
    c) Dibucaine
    d) Bupivacaine
  39. Which of the following local anesthetics is called a universal anesthetic?
    a) Procaine
    b) Ropivacaine
    c) Lidocaine
    d) Bupivacaine
  40. Most serious toxic reaction to local anesthetics is:
    a) Seizures
    b) Cardiovascular collapse
    c) Respiratory failure
    d) All of the above
  41. Correct statements concerning cocaine include all of the following EXCEPT:
    a) Cocaine is often used for nose and throat procedures
    b) Limited use because of abuse potential
    c) Myocardial depression and peripheral vasodilatation
    d) Causes sympathetically mediated tachycardia and vasoconstriction
  42. Which of the following local anesthetics is more cardiotoxic?
    a) Procaine
    b) Bupivacaine
    c) Lidocaine
    d) Mepivacaine
  43. Most local anesthetics can cause:
    a) Depression of abnormal cardiac pacemaker activity, excitability, conduction
    b) Depression of the strength of cardiac contraction
    c) Cardiovascular collapse
    d) All of the above
  44. Which one of the following local anesthetics causes methemoglobinemia?
    a) Prilocaine
    b) Procaine
    c) Lidocaine
    d) Ropivacaine
  45. Procaine has all of the following properties EXCEPT:
    a) It has ester linkage
    b) Its metabolic product can inhibit the action of sulfonamides
    c) It readily penetrates the skin and mucosa
    d) It is relatively short-acting
  46. Correct statements concerning lidocaine include all of the following EXCEPT:
    a) It is an universal anesthetic
    b) It has esteratic linkage
    c) It widely used as an antiarrhythmic agent
    d) It is metabolized in liver
  47. Which of the following local anesthetics is more likely to cause allergic reactions?
    a) Lidocaine
    b) Bupivacaine
    c) Procaine
    d) Ropivacaine
  48. Tetracaine has all of the following properties EXCEPT:
    a) Slow onset
    b) Low potency
    c) Long duration
    d) High toxicity
  49. Correct statements concerning bupivacaine include all of the following EXCEPT:
    a) It has low cardiotoxicity
    b) It has amide linkage
    c) It is a long-acting drug
    d) An intravenous injection can lead to seizures

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Anesthesia MCQs with Answers Free 2022 : ANSWER KEY

If you find any Question or Answer wrong , then you can mention in the comment below.

01. –   b   11. –   b   21. –   c   31. –   b    41. –  c
02. –   c   12. –   c   22. –   a   32. –   c    42. –  b
03. –   d   13. –   b   23. –   d   33. –   d   43. –  d
04. –   a   14. –   a   24. –   b   34. –   b   44. –  a
05. –   b   15. –   d   25. –   c   35. –   a   45. –  c
06. –   c   16. –   b   26. –   a   36. –   b   46. –  b
07. –   b   17. –   a   27. –   b   37. –   d   47. –  c
08. –   c   18. –   c   28. –   d   38. –   a   48. –  b
09. –   d   19. –   b   29. –   d   39. –   c   49. –  a
10. –   c   20. –   d   30. –   a   40. –   d

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