Antibiotics MCQs with Answers Free 2022

Practice these Multiple Choice Questions that can be very useful for following Examinations like GPAT, NIPER, B- Pharma , D-Pharma etc. In this Series of Practice you will get a lots of Topic-wise Multiple Choice Questions regarding your Exams. If you haven’t find MCQ post regarding any topic, what you want then feel free to mention below . Now Practice Antibiotics MCQs in this post.

IMG 20220630 185020 453 compress96

An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. 


Antibiotics MCQs with Answers Free 2022 [Practice Now]


  1. What does the term “antibiotics” mean:
    a) Non-organic or synthetic substances that selectively kill or inhibit the growth of other microorganisms
    b) Substances produced by some microorganisms and their synthetic analogues that selectively kill or inhibit
    the growth of another microorganisms
    c) Substances produced by some microorganisms and their synthetic analogues that inhibit the growth of organism cells
    d) Synthetic analogues of natural substances that kill protozoa and helminthes
  2. General principles of anti-infective therapy are:
    a) Clinical judgment of microbiological factors
    b) Definitive identification of a bacterial infection and the microorganism’s susceptibility
    c) Optimal route of administration, dose, dosing frequency and duration of treatment
    d) All of the above
  3. Minimal duration of antibacterial treatment usually is:
    a) Not less than 1 day
    b) Not less than 5 days
    c) Not less than 10-14 days
    d) Not less than 3 weeks
  4. Rational anti-microbial combination is used to:
    a) Provide synergism when microorganisms are not effectively eradicated with a single agent alone
    b) Provide broad coverage
    c) Prevent the emergence of resistance
    d) All of the above
    125
  5. Mechanisms of bacterial resistance to anti-microbial agents are the following, EXCEPT:
    a) Active transport out of a microorganism or/and hydrolysis of an agent via enzymes produced by a microorganism
    b) Enlarged uptake of the drug by a microorganism
    c) Modification of a drug’s target
    d) Reduced uptake by a microorganism
  6. The statement, that some microorganisms can develop alternative metabolic pathways for rendering reactions inhibited
    by the drug, is:
    a) True
    b) False
  7. All of the following drugs are antibiotics, EXCEPT:
    a) Streptomycin
    b) Penicillin
    c) Co-trimoxazole
    d) Chloramphenicol
  8. Bactericidal effect is:
    a) Inhibition of bacterial cell division
    b) Inhibition of young bacterial cell growth
    c) Destroying of bacterial cells
    d) Formation of bacterial L-form
  9. Which of the following groups of antibiotics demonstrates a bactericidal effect?
    a) Tetracyclines
    b) Macrolides
    c) Penicillins
    d) All of the above
  10. Bacteristatic effect is:
    a) Inhibition of bacterial cell division
    b) Inhibition of young bacterial cells growth
    c) Destroying of bacterial cells
    d) Formation of bacterial L-form
  11. Which of the following groups of antibiotics demonstrates a bacteristatic effect:
    a) Carbapenems
    b) Macrolides
    c) Aminoglycosides
    d) Cephalosporins
  12. Which of the following antibiotics contains a beta-lactam ring in their chemical structure :
    a) Penicillins
    b) Cephalosporins
    c) Carbapenems and monobactams
    d) All groups
  13. Tick the drug belonging to antibiotics-macrolides:
    a) Neomycin
    b) Doxycycline
    c) Erythromycin
    d) Cefotaxime
  14. Tick the drug belonging to antibiotics-carbapenems:
    a) Aztreonam
    b) Amoxacillin
    c) Imipinem
    d) Clarithromycin
  15. Tick the drug belonging to antibiotics-monobactams:
    a) Ampicillin
    b) Bicillin-5
    c) Aztreonam
    d) Imipinem
  16. Tick the drug belongs to antibiotics-cephalosporins:
    a) Streptomycin
    b) Cefaclor
    c) Phenoxymethilpenicillin
    d) Erythromycin
  17. Tick the drug belonging to lincozamides:
    a) Erythromycin
    126
    b) Lincomycin
    c) Azithromycin
    d) Aztreonam
  18. Tick the drug belonging to antibiotics-tetracyclines:
    a) Doxycycline
    b) Streptomycin
    c) Clarithromycin
    d) Amoxacillin
  19. All of antibiotics are aminoglycosides, EXCEPT:
    a) Gentamycin
    b) Streptomycin
    c) Clindamycin
    d) Neomycin
  20. Tick the drug belonging to nitrobenzene derivative:
    a) Clindamycin
    b) Streptomycin
    c) Azithromycin
    d) Chloramphenicol
  21. Tick the drug belonging to glycopeptides:
    a) Vancomycin
    b) Lincomycin
    c) Neomycin
    d) Carbenicillin
  22. Antibiotics inhibiting the bacterial cell wall synthesis are:
    a) Beta-lactam antibiotics
    b) Tetracyclines
    c) Aminoglycosides
    d) Macrolides
  23. Antibiotic inhibiting bacterial RNA synthesis is:
    a) Erythromycin
    b) Rifampin
    c) Chloramphenicol
    d) Imipinem
  24. Antibiotics altering permeability of cell membranes are:
    a) Glycopeptides
    b) Polymyxins
    c) Tetracyclines
    d) Cephalosporins
  25. All of the following antibiotics inhibit the protein synthesis in bacterial cells, EXCEPT:
    a) Macrolides
    b) Aminoglycosides
    c) Glycopeptides
    d) Tetracyclines
  26. Biosynthetic penicillins are effective against:
    a) Gram-positive and gram-negative cocci, Corynebacterium diphtheria, spirochetes, Clostridium gangrene
    b) Corynebacterium diphtheria, mycobacteries
    c) Gram positive cocci, viruses
    d) Gram negative cocci, Rickettsia, mycotic infections
  27. Which of the following drugs is a gastric acid resistant:
    a) Penicillin G
    b) Penicillin V
    c) Carbenicillin
    d) Procain penicillin
  28. Which of the following drugs is penicillinase resistant:
    a) Oxacillin
    b) Amoxacillin
    c) Bicillin-5
    d) Penicillin G
  29. All of the following drugs demonstrate a prolonged effect, EXCEPT:
    a) Penicillin G
    b) Procain penicillin
    127
    c) Bicillin-1
    d) Bicillin-5
  30. Mechanism of penicillins’ antibacterial effect is:
    a) Inhibition of transpeptidation in the bacterial cell wall
    b) Inhibition of beta-lactamase in the bacterial cell
    c) Activation of endogenous proteases, that destroy bacterial cell wall
    d) Activation of endogenous phospholipases, which leads to alteration of cell membrane permeability
  31. Pick out the beta-lactamase inhibitor for co-administration with penicillins:
    a) Clavulanic acid
    b) Sulbactam
    c) Tazobactam
    d) All of the above
  32. Cephalosporines are drugs of choice for treatment of:
    a) Gram-positive microorganism infections
    b) Gram-negative microorganism infections
    c) Gram-negative and gram-positive microorganism infections, if penicillins have no effect
    d) Only bacteroide infections
  33. Carbapenems are effective against:
    a) Gram-positive microorganisms
    b) Gram-negative microorganisms
    c) Only bacteroide infections
    d) Broad-spectum
  34. All of the following antibiotics are macrolides, EXCEPT:
    a) Erythromycin
    b) Clarithromycin
    c) Lincomycin
    d) Roxythromycin
  35. Tetracyclins have following unwanted effects:
    a) Irritation of gastrointestinal mucosa, phototoxicity
    b) Hepatotoxicity, anti-anabolic effect
    c) Dental hypoplasia, bone deformities
    d) All of the above
  36. Tick the drug belonging to antibiotics-aminoglycosides:
    a) Erythromycin
    b) Gentamycin
    c) Vancomycin
    d) Polymyxin
  37. Aminoglycosides are effective against:
    a) Gram positive microorganisms, anaerobic microorganisms, spirochetes
    b) Broad-spectum, except Pseudomonas aeruginosa
    c) Gram negative microorganisms, anaerobic microorganisms
    d) Broad-spectum, except anaerobic microorganisms and viruses
  38. Aminoglycosides have the following unwanted effects:
    a) Pancytopenia
    b) Hepatotoxicity
    c) Ototoxicity, nephrotoxicity
    d) Irritation of gastrointestinal mucosa
  39. Choose the characteristics of chloramphenicol:
    a) Broad-spectum. Demonstrates a bactericidal effect.
    b) Influences the Gram-positive microorganisms. Demonstrates a bactericidal effect.
    c) Influences the Gram-negative microorganisms. Demonstrates a bactericidal effect.
    d) Broad-spectum. Demonstrates a bacteristatic effect.
  40. Chloramphenicol has the following unwanted effects:
    a) Nephrotoxicity
    b) Pancytopenia
    c) Hepatotoxicity
    d) Ototoxicity
  41. Choose the characteristics of lincozamides:
    a) Broad-spectum. Demonstrates a bactericidal effect.
    b) Influence mainly the anaerobic organisms, Gram negative cocci.
    c) Broad-spectum. Demonstrates a bacteristatic effect.
    128
    d) Influence mainly the anaerobic organisms, Gram positive cocci.
  42. Lincozamides have the following unwanted effect:
    a) Nephrotoxicity
    b) Cancerogenity
    c) Pseudomembranous colitis
    d) Irritation of respiratory organs
  43. Choose the characteristics of vancomicin:
    a) It is a glycopeptide, inhibits cell wall synthesis active only against Gram-negative bacteria
    b) It is a glycopeptide, that alters permeability of cell membrane and is active against anaerobic bacteria
    c) It is a beta-lactam antibiotic, inhibits cell wall synthesis active only against Pseudomonas aeruginosa
    d) It is a glycopeptide, inhibits cell wall synthesis and is active only against Gram-positive bacteria.
  44. Vancomicin has the following unwanted effects:
    a) Pseudomembranous colitis
    b) Hepatotoxicity
    c) “Red neck” syndrome, phlebitis
    d) All of the above
  45. Which of the following drugs is used for systemic and deep mycotic infections treatment:
    a) Co-trimoxazol
    b) Griseofulvin
    c) Amphotericin B
    d) Nitrofungin
  46. Which of the following drugs is used for dermatomycosis treatment:
    a) Nystatin
    b) Griseofulvin
    c) Amphotericin B
    d) Vancomycin
  47. Which of the following drugs is used for candidiasis treatment:
    a) Griseofulvin
    b) Nitrofungin
    c) Myconazol
    d) Streptomycin
  48. All of the following antifungal drugs are antibiotics, EXCEPT:
    a) Amphotericin B
    b) Nystatin
    c) Myconazol
    d) Griseofulvin
  49. Mechanism of Amphotericin B action is:
    a) Inhibition of cell wall synthesis
    b) Inhibition of fungal protein synthesis
    c) Inhibition of DNA synthesis
    d) Alteration of cell membrane permeability
  50. Azoles have an antifungal effect because of:
    a) Inhibition of cell wall synthesis
    b) Inhibition of fungal protein synthesis
    c) Reduction of ergosterol synthesis
    d) Inhibition of DNA synthesis
  51. Which of the following drugs alters permeability of Candida cell membranes:
    a) Amphotericin B
    b) Ketoconazole
    c) Nystatin
    d) Terbinafine
  52. Amfotericin B has the following unwanted effects:
    a) Psychosis
    b) Renal impairment, anemia
    c) Hypertension, cardiac arrhythmia
    d) Bone marrow toxicity
  53. Tick the drug belonging to antibiotics having a polyene structure:
    a) Nystatin
    b) Ketoconazole
    c) Griseofulvin
    d) All of the above
    129
  54. All of the following drugs demonstrate a fungicidal effect, EXCEPT:
    a) Terbinafin
    b) Amfotericin B
    c) Ketoconazole
    d) Myconazol
  55. Characteristics of polyenes are following, except:
    a) Alter the structure and functions of cell membranes
    b) Broad-spectrum
    c) Fungicidal effect
    d) Nephrotoxicity, hepatotoxicity
  56. Characteristics of Amfotericin B are following, EXCEPT:
    a) Used for systemic mycosis treatment
    b) Poor absorption from the gastro-intestinal tract
    c) Does not demonstrate nephrotoxicity
    d) Influences the permeability of fungus cell membrane

Hope you liked the above content about Antibiotics MCQs with Answers Free 2022. For more content like this visit our Website “ExamFlame” . Also you can also request the material you want in the comment section . Don’t forget to turn on the website’s notification to get regular updates, important information and various study material regarding your exams.

NOTE : – If you need anything else more like e-books, video lectures, syllabus  etc regarding  your Preparation / Examination  then do 📌 mention in the Comment Section below. 

Antibiotics MCQs with Answers Free 2022 : ANSWER KEY

If you find any Question or Answer wrong , then you can mention in the comment below.

01. –   b   11. –   b   21. –   a   31. –   d     41. –  d     51. –  c
02. –   d   12. –   d   22. –   a   32. –   c     42. –  c     52. –  b
03. –   b   13. –   c   23. –   b   33. –   d     43. –  d     53. –  a
04. –   d   14. –   c   24. –   b   34. –   c     44. –   c     54. –  b
05. –   b   15. –   c   25. –   c   35. –   d     45. –  c      55. –  c
06. –   a   16. –   b   26. –   a   36. –   b     46. –  b      56. –  c
07. –   c   17. –   b   27. –   b   37. –   d     47. –  c  
08. –   c   18. –   a   28. –   a   38. –   c     48. –  c  
09. –   c   19. –   c   29. –   a   39. –   a      49. –  d 
10. –   a   20. –   d   30. –   a   40. –   b     50. –  c

Searches and Tags

  • Antibiotics MCQ PDF
  • Antibiotic Question Bank
  • MCQs on cephalosporins
  • MCQ on antibiotics Medicinal Chemistry
  • Tetracycline MCQ questions and answers
  • mcq on beta-lactam antibiotics
  • Penicillin MCQ PDF
  • Antibiotics MCQ GPAT
  • MCQ on penicillin production
  • What is meant by antibiotic resistance mcq
  • Antibiotics are used to treat infections by
  • The yield of the antibiotic depends upon
  • Which of the following species is used for producing streptomycin
  • In which of the following substances is chlortetracycline soluble

Leave a Comment

close