GPAT Pharmaceutics Syllabus PDF Download | GPAT Pharmaceutics Syllabus download
Download GPAT Pharmaceutics Syllabus
Download GPAT Pharmaceutics Syllabus PDF – In this post of Syllabus we elaborate the Pharmaceutics Syllabus of GPAT which is a national level competitive exam through which Students can get admission in Pharmacy courses in different colleges and universities across the country. We all know the importance of syllabus for any exam or course, this is the only thing which gives us a right path to study for the exam in other word we can say Syllabus is one of the most important tool to crack any examination, because it gives you the exact and proper Orientation of what to study or how much you have to study for the exam. So , here you will get the detailed GPAT Pharmaceutics Syllabus .
The major topics contains in GPAT Pharmaceutics Syllabus are Pharmacy Profession & Introduction to Pharmaceuticals, Introduction to dosage form, Sources of drug information, Allopathic dosage form, Crude extract, Allergenic extract, Biological products, Pharmaceutical Plant, location, layout, Dosage Form Necessities and Additives, Powders, Capsules, Tablets, Parenterals – product requiring sterile packaging , Suspensions, Emulsions, Suppositories, Semisolids, Liquids (solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses), Pharmaceutical Aerosols, Ophthalmic preparations, Preformulations, Stability of formulated products, Prolonged Action Pharmaceuticals, Novel Drug delivery system, GMP and Validation, Packaging Materials, Cosmetics and Pilot plant scale-up techniques. Below the full detailed GPAT Pharmaceutical Analysis Syllabus is given : –
Detailed GPAT Pharmaceutics Analysis Syllabus
1. Pharmacy Profession & Introduction to Pharmaceuticals
Pharmacy as a career, evaluation of Pharmacy, earlier period middle to modern ages. Definition, importance of pharmaceuticals, areas concerned, scope of Pharmaceutics, history and development of the profession of Pharmacy and Pharmaceutical industry in India. A brief review of present Indian Pharma. Industry in global perspective.
2. Introduction to dosage form
Definition of the drug. New drug and dosage form. The desirable properties of a dosage form, the need of dosage form. Ideas about the available type of dosage forms and new drug delivery system.
3. Sources of drug information
Introduction to Pharmacopoeia with reference to IP, BP, USP and International Pharmacopeia. Study of structure/features (index) general notice and compartment of monographs of excipients, drug and drug product. Other sources. Textbooks, journals, internet (drug information system, online database, patient/ consumer information and non- print material. Classification of information, primary, secondary and tertiary. Nomenclature of the drug.
4. Allopathic dosage form
Merits/demerits, importance, formulation development – vehicles/excipients with examples for the dosage form: liquid dosage form: monophasic liquid dosage form. Aromatic waters, syrup, elixir, linctus, lotion, liniment, glycerites, solutions, spirits, ENT preparations, mixtures, paints, mouthwash.
5. Crude extract
Infusion, decoction, maceration, percolation, tincture and extract. Methods of preparations of dry, soft and liquid extract.
6. Allergenic extract
Types of allergens, preparation of extract, testing and standardization of extracts.
7. Biological products
Absorbable and non-absorbable material types, sutures and ligatures, processing, manufacturing, sterilization, packing, QC tests of materials like catgut and nylon.
8. Pharmaceutical Plant, location, layout
Plant location and layout of an industry. Various factors affecting locational aspects of chemical and pharmaceutical plants. The layout of plant building and importance of flow sheet, the difference between scientific process and technological process, the layout of various departments, equipment, and product layout v/s process layout.
9. Dosage Form Necessities and Additives
Antioxidants, preservatives, coloring agents, flavoring agents and diluting agents, emulsifying agents, suspending agents, ointment bases, solvents, and others.
Advantages and limitations as dosage form, manufacturing procedure and equipment, special care and problems in manufacturing powders, powders of IP, effervescent granules and salts.
Hard gelatin capsules, shell formulation and manufacturing, capsule sizes, storage, filing, cleaning process general formulation contents and evaluation. Soft gelatin capsules, shell formulation, formulation contents, filing, sealing and storage. Microencapsulation, advantages, encapsulation materials, methods of microencapsulation, I.P. formulations
Types, ideal requirement, classification, granulation methods, general formulation, compression machines, different types of tooling’s, difficulties in tableting, troubleshooting aspects, evaluation, sugar coating, compression coating, film coating, problems in tablet
coatings and their troubleshooting aspects. IP formulations.
13. Parenterals – product requiring sterile packaging
Definition, types advantages and limitations, general formulation, vehicles, production procedure, production facilities, controls, tests, selected IP injections, sterile powders, implants, emulsions, suspensions.
Formulation of deflocculated and flocculated suspension, manufacturing procedure, evaluation methods, IP suspensions.
Types, emulsifying agents, general formulation, manufacturing procedure, evaluation methods, IP emulsions.
Ideal requirements, bases, manufacturing procedure, evaluation methods, IP products.
Definitions, bases, general formulation, manufacturing procedure, evaluation methods, IP products.
18. Liquids(solutions, syrups, elixirs, spirits, aromatic water, liquid for external uses)
Definition, types, general formulation, manufacturing procedure, evaluation methods, IP products.
19. Pharmaceutical Aerosols
Definition, propellants, general formulation, manufacturing and packaging methods, pharmaceutical applications. Impacts of propellants on the environment.
20. Ophthalmic preparations
Requirement, formulation, methods of preparation, containers, evaluation, IP products.
Consideration of Importance, physical properties, physical forms, particle size, crystal forms, bulk control, solubility, wetting, flow cohesiveness, compressibility, organoleptic properties and its effect on final product consideration of Chemical properties, hydrolysis, oxidation, recemization, polymerization, isomerization, decarboxylation, enzymatic decomposition, formulation additives, stabilizers, suspending and dispersing agents dyes, solid excipients etc. and its effect on quality of finished product.
22. Stability of formulated products
Requirements, drug regulatory aspects, pharmaceutical products stability, shelf life, overages, containers, closures. Reaction rate and order, acid-base catalysis, destabilization and accelerated stability testing.
23. Prolonged Action Pharmaceuticals
Benefits, limitations, oral products, terminology, drug elimination rate, types and construction of implants products, product evaluation, parenteral products, absorption and evaluation.
24. Novel Drug delivery system
Critical fluid technology, transdermal drug delivery system, controlled drug delivery system, multiple emulsion, nanoparticles, targeted drug delivery system, aerosols, inhalation & new products reported etc.
25. GMP and Validation
Introduction to GMP, QC and QA. Concept and need of good manufacturing practice guidelines. Elements of GMP covering controls of area and processes and product. Regulations related to GMP. Introduction of the validation process. Types of validation. The brief methodology of process, equipment and instrument validation.
26. Packaging Materials
Role and features of Pharmaceutical packing materials. Glass, plastic, rubber, metal and paper as pharmaceutical packaging material. General quality control of pharmaceutical packages. Primary, secondary and tertiary packaging materials. Child resistant and pilfer-proof packaging.
Formulation and preparation of dentifrices, hair creams, lipsticks, face powders, shaving preparations, skin creams, shampoos, hair dyes, depilatories, manicure preparations etc.
28. Pilot plant scale-up techniques
Need, organization and layout, scale-up techniques for solid and liquid dosage forms. Technology transfer.
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