GPAT Pharmacology Syllabus PDF Download | GPAT Pharmacology Syllabus download
Download GPAT Pharmacology Syllabus
In this Syllabus post of Pharmacology for GPAT exam , which is a national level entrance exam for those students who want to take admission into a good college or university across the country for Pharmacy courses. GPAT stands for Graduate Pharmacy Aptitude Test so only those students are eligible for this entrance test who have done their graduation with a good marks form Science stream. So, for every exam syallbus is one the primary thing to crack the exam, that’s why here you will get GPAT Pharmacology Syllabus in very detailed form.
The major topics contains in GPAT Pharmacology Syllabus are General Pharmacology, Nerohumoral transmission in autonomic and central nervous system, Pharmacology of peripheral nervous system, Pharmacology of central nervous System, Pharmacology of cardiovascular system, Drugs acting on urinary system, Drugs acting on Respiratory system, Pharmacology of Endocrine system, ChemotherapyAutacoids and their Antagonists, Pharmacology of drug acting on the gastrointestinal tract, Chronopharmacology, Immnopharmacology, Vitamins & Minerals and Principles of toxicology. Below the full detailed GPAT Pharmaceutical Analysis Syllabus is given : –
Detailed GPAT Pharmacology Syllabus
1. General Pharmacology
Introduction to Pharmacology- Definition, scope and source of drugs, dosage forms and routes of drug administration. Pharmacodynamics-Mechanism of drug action, Receptors, classification and drug-receptor interactions, combined effects of drugs, factors modifying drug actions.
Pharmacokinetics-Mechanism and principle of absorption, distribution, metabolism and excretion of drugs. Principles of basic and clinical pharmacokinetics. Pharmacogenetics. Adverse drug reactions.Discovery and development of new drugs-Preclinical and clinical studies.
Detailed pharmacology including classification, mechanism of action and therapeutic uses of following classes:
2. Nerohumoral transmission in autonomic and central nervous system:
Neurohumoral transmission (Autonomic and somatic). Neurohumoral transmission in the C.N.S with special emphasis on Pharmacology of various neurotransmitters. Nitric oxide: Biosynthesis of nitric oxide and its physiological role.Therapeutic use of nitric oxide and nitric oxide donors. Clinical condition in which nitric
oxide may play a part.
Peptides and proteins as mediators: General Principal of peptide pharmacology Biosynthesis and regulation of peptides Peptide antagonists. Protein and peptide as drugs.
3. Pharmacology of peripheral nervous system
Parasympathomimetics, Parasympatholytics, Sympathomimetics, Sympatholytics, Ganglionic stimulants and blockers. Neuromuscular blocking agents and skeletal muscle relaxants (peripheral). Local anesthetic agents. Drugs used in Myasthenia Gravis.
4. Pharmacology of central nervous System
General anesthetics. Alcohols and disulfiram. Sedatives, hypnotics and centrally acting muscle relaxants, Psychopharmacological agents: Antipsychotics, antidepressants, antianxiety agents, anti-manics and hallucinogens. Anti-epileptic drugs. Anti-parkinsonism drugs. Nootropics. Narcotic analgesics, drug addiction, drug abuse, tolerance and dependence.
5. Pharmacology of cardiovascular system
Introduction of hemodynamics and Electrophysiology of heart. Anti-hypertensive drugs, Anti-anginal agents, Anti-arrhythmic drugs.Drugs used in congestive heart failure. Anti-hyperlipidemic drugs. Drugs used in the therapy of shock. Haematinics, anticoagulants and haemostatic agents. Fibrinolytics and antiplatelet drugs. Blood and plasma volume expanders.
6. Drugs acting on urinary system
Diuretics and anti-diuretics.
7. Drugs acting on Respiratory system
Anti-asthmatic drugs, Mucolytics and nasal decongestants, Anti-tussives and expectorants. Respiratory stimulants
8. Pharmacology of Endocrine system
Basic concepts in endocrine pharmacology. Hypothalamic and pituitary hormones. Thyroid hormones and antithyroid drugs, Parathormone, Calcitonin and vitamin-D. Insulin, oral hypoglycemic agents and glucagon. ACTH and corticosteroids. Androgens and anabolic steroids. Estrogens, progesterone and oral contraceptives. Drugs acting on the uteru.
General principles of chemotherapy. Sulphonamides and co-trimoxazole.Antibiotics- Penicillins, cephalosporins, chloramphenicol, Macrolides, quinolones and fluoroquinolons,. Tetracyclines. Aminoglycosides and miscellaneous antibiotics. Chemotherapy of tuberculosis, leprosy, fungal diseases, viral diseases, AIDS, protozoal
diseases, worm infections, urinary tract infections and sexually transmitted diseases. Chemotherapy of malignancy.
10. Autacoids and their Antagonists
Histamine, 5-HT and their agonsists and antagonists.
Prostaglandins, thromboxanes and leukotrienes. pentagastrin, cholecystokinin, angiotensin, bradykinin and substance P.,Analgesic, anti-pyretic, anti – inflammatory and anti-gout drugs.
11. Pharmacology of drug acting on the gastrointestinal tract
Antacids, anti-secretary and antiulcer drugs. Laxatives and antidiarrheal drugs. Appetite stimulants and suppressants. Digestants and carminatives. Emetics and anti-emetics.
Definition of rhythm and cycles. Biological clocks and their significance leading to chronotherapy.
Immunostimulants and immunosuppressants.
14. Vitamins & Minerals
Vitamin deficiency diseases and their management. Role of minerals in health & diseases.
15. Principles of toxicology
Definition of poison. General principles of treatment of Poisoning. Treatment of poisoning due to Heavy metals, insecticides, opioids and other addict forming drugs. Study of acute, sub acute and chronic toxicity as per OECD guidelines (guidelines 420, 423, 425, 407, 408, 451/452; only names and significance, detailed procedures and minute details are not expected).
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Download GPAT Previous Year Question Paper pdf with Solutions [1998-2022] free
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How many times GPAT can be written?
Any times, there is no age restrictions. Qualification is B. Pharmacy completed, final year candidates also can apply. Qualified candidates will get 12000 per month upto 24 months.
What comes after qualifying GPAT?
On the basis of cutoff scores of GPAT, participating institutes will conduct the counselling process for granting M. Pharm admission. conducted by All India Council for Technical Education (AICTE) for admissions to Masters M. Pharma programmes in the country.
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