Narcotics Analgesics MCQs with Answers Free 2022

Narcotic analgesics are prescription pain relievers ordered fortreatment of moderate pain to severe pain. They are most appropriately prescribed for the relief of short-term, intense discomfort due to medical conditions or pain occurring immediately after surgery.

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Narcotics Analgesics MCQs with Answers Free 2022 [Practice Now]


  1. Narcotics analgesics should:
    a) Relieve severe pain
    b) Induce loss of sensation
    c) Reduce anxiety and exert a calming effect
    d) Induce a stupor or somnolent state
  2. Second-order pain is:
    a) Sharp, well-localized pain
    b) Dull, burning pain
    c) Associated with fine myelinated A-delta fibers
    d) Effectively reduced by non-narcotic analgesics
  3. Chemical mediators in the nociceptive pathway are all of the following EXCEPT:
    a) Enkephalins
    b) Kinins
    c) Prostaglandins
    d) Substance P
  4. Indicate the chemical mediator in the antinociceptive descending pathways:
    a) BETA-endorphin
    b) Met- and leu-enkephalin
    c) Dynorphin
    d) All of the above
  5. 5. Which of the following mediators is found mainly in long descending pathways from the midbrain to the dorsal horn?
    a) Prostaglandin E
    b) Dynorphin
    c) Enkephalin
    d) Glutamate
  6. Select the brain and spinal cord regions, which are involved in the transmission of pain?
    a) The limbic system, including the amygdaloidal nucleus and the hypothalamus
    b) The ventral and medial parts of the thalamus
    c) The substantia gelatinosa
    d) All of the above
  7. Mu (μ) receptors are associated with:
    a) Analgesia, euphoria, respiratory depression, physical dependence
    b) Spinal analgesia, mydriasis, sedation, physical dependence
    c) Dysphoria, hallucinations, respiratory and vasomotor stimulation
    d) Analgesia, euphoria, respiratory stimulation, physical dependence
  8. Which of the following opioid receptor types is responsible for euphoria and respiratory depression?
    a) Kappa-receptors
    b) Delta-receptors
    c) Mu-receptors
    d) All of the above
  9. Indicate the opioid receptor type, which is responsible for dysphoria and vasomotor stimulation:
    a) Kappa-receptors
    b) Delta-receptors
    c) Mu-receptors
    d) All of the above
  10. Kappa and delta agonists:
    a) Inhibit postsynaptic neurons by opening K+
    channels
    b) Close a voltage-gated Ca2+ channels on presynaptic nerve terminals
    c) Both a and b
    d) Inhibit of arachidonate cyclooxygenase in CNS
  11. Which of the following supraspinal structures is implicated in pain-modulating descending pathways?
    a) The midbrain periaqueductal gray
    b) The hypothalamus
    c) The aria postrema
    d) The limbic cortex
  12. Indicate the neurons, which are located in the locus ceruleus or the lateral tegmental area of the reticular formation:
    a) Dopaminergic
    b) Serotoninergic
    c) Nonadrenergic
    d) Gabaergic
    47
  13. Which of the following analgesics is a phenanthrene derivative?
    a) Fentanyl
    b) Morphine
    c) Methadone
    d) Pentazocine
  14. Tick narcotic analgesic, which is a phenylpiperidine derivative:
    a) Codeine
    b) Dezocine
    c) Fentanyl
    d) Buprenorphine
  15. Which of the following opioid analgesics is a strong mu receptor agonist?
    a) Naloxone
    b) Morphine
    c) Pentazocine
    d) Buprenorphine
  16. Indicate the narcotic analgesic, which is a natural agonist:
    a) Meperidine
    b) Fentanyl
    c) Morphine
    d) Naloxone
  17. Select the narcotic analgesic, which is an antagonist or partial mu receptor agonist:
    a) Fentanyl
    b) Pentazocine
    c) Codeine
    d) Methadone
  18. Which of the following agents is a full antagonist of opioid receptors?
    a) Meperidine
    b) Buprenorphine
    c) Naloxone
    d) Butorphanol
  19. The principal central nervous system effect of the opioid analgesics with affinity for a mu receptor is:
    a) Analgesia
    b) Respiratory depression
    c) Euphoria
    d) All of the above
  20. Which of the following opioid analgesics can produce dysphoria, anxiety and hallucinations?
    a) Morphine
    b) Fentanyl
    c) Pentazocine
    d) Methadone
  21. Indicate the opioid analgesic, which has 80 times analgesic potency and respiratory depressant properties of morphine,
    and is more effective than morphine in maintaining hemodynamic stability?
    a) Fentanyl
    b) Pentazocine
    c) Meperidine
    d) Nalmefene
  22. Which of the following opioid analgesics is used in combination with droperidol in neuroleptanalgesia?
    a) Morphine
    b) Buprenorphine
    c) Fentanyl
    d) Morphine
  23. Fentanyl can produce significant respiratory depression by:
    a) Inhibiting brain stem respiratory mechanisms
    b) Suppression of the cough reflex leading to airway obstruction
    c) Development of truncal rigidity
    d) Both a and c
  24. Most strong mu receptor agonists cause:
    a) Hypertension
    b) Increasing the pulmonary arterial pressure and myocardial work
    c) Cerebral vasodilatation, causing an increase in intracranial pressure
    d) All of the above
    48
  25. Which of the following opioid analgesics can produce an increase in the pulmonary arterial pressure and myocardial
    work?
    a) Morphine
    b) Pentazocine
    c) Meperidine
    d) Methadone
  26. Morphine causes the following effects EXCEPT:
    a) Constipation
    b) Dilatation of the biliary duct
    c) Urinary retention
    d) Bronchiolar constriction
  27. Therapeutic doses of the opioid analgesics:
    a) Decrease body temperature
    b) Increase body temperature
    c) Decrease body heat loss
    d) Do not affect body temperature
  28. Which of the following opioid analgesics is used in obstetric labor?
    a) Fentanyl
    b) Pentazocine
    c) Meperidine
    d) Buprenorphine
  29. Indicate the opioid analgesic, which is used for relieving the acute, severe pain of renal colic:
    a) Morphine
    b) Naloxone
    c) Methadone
    d) Meperidine
  30. Which of the following opioid analgesics is used in the treatment of acute pulmonary edema?
    a) Morphine
    b) Codeine
    c) Fentanyl
    d) Loperamide
  31. The relief produced by intravenous morphine in dyspnea from pulmonary edema is associated with reduced:
    a) Perception of shortness of breath
    b) Patient anxiety
    c) Cardiac preload (reduced venous tone) and afterload (decreased peripheral resistance)
    d) All of the above
  32. Rhinorrhea, lacrimation, chills, gooseflesh, hyperventilation, hyperthermia, mydriasis, muscular aches, vomiting,
    diarrhea, anxiety, and hostility are effects of:
    a) Tolerance
    b) Opioid overdosage
    c) Drug interactions between opioid analgesics and sedative-hypnotics
    d) Abstinence syndrome
  33. The diagnostic triad of opioid overdosage is:
    a) Mydriasis, coma and hyperventilation
    b) Coma, depressed respiration and miosis
    c) Mydriasis, chills and abdominal cramps
    d) Miosis, tremor and vomiting
  34. Which of the following opioid agents is used in the treatment of acute opioid overdose?
    a) Pentazocine
    b) Methadone
    c) Naloxone
    d) Remifentanyl
  35. Indicate the pure opioid antagonist, which has a half-life of 10 hours:
    a) Naloxone
    b) Naltrexone
    c) Tramadol
    d) Pentazocine
  36. In contrast to morphine, methadone:
    a) Causes tolerance and physical dependence more slowly
    b) Is more effective orally
    c) Withdrawal is less severe, although more prolonged
    49
    d) All of the above
  37. Which of the following opioid analgesics is a partial mu receptor agonist?
    a) Morphine
    b) Methadone
    c) Buprenorphine
    d) Sufentanyl
  38. Indicate a partial mu receptor agonist, which has 20-60 times analgesic potency of morphine, and a longer duration of
    action:
    a) Pentazocine
    b) Buprenorphine
    c) Nalbuphine
    d) Naltrexone
  39. Which of the following opioid analgesics is a strong kappa receptor agonist and a mu receptor antagonist?
    a) Naltrexone
    b) Methadone
    c) Nalbuphine
    d) Buprenorphine
  40. Which of the following drugs has weak mu agonist effects and inhibitory action on norepinephrine and serotonin reuptake
    in the CNS?
    a) Loperamide
    b) Tramadol
    c) Fluoxetine
    d) Butorphanol

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Narcotics Analgesics MCQs with Answers Free 2022 : ANSWER KEY

If you find any Question or Answer wrong , then you can mention in the comment below.

01. –   a   11. –   a   21. –   a   31. –   d    
02. –   b   12. –   c   22. –   c   32. –   d    
03. –   a   13. –   b   23. –   d   33. –   b    
04. –   d   14. –   c   24. –   c   34. –   c   
05. –   c   15. –   b   25. –   b   35. –   b  
06. –   d   16. –   c   26. –   b   36. –   b   
07. –   a   17. –   b   27. –   a   37. –   c   
08. –   c   18. –   c   28. –   c   38. –   b  
09. –   a   19. –   d   29. –   d   39. –   c  
10. –   b   20. –   c   30. –   a   40. –   b   

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